Results of two variants can be compared in the chart manager. Results from two different variants can be displayed on the diagram in one result label. The diagrams of different projects and variants can be displayed at the same time Variants can be compared, merged and deleted. In the variant data, only the differences from the parent variant are saved. For each network you can define and store any desired number of variants and subvariants (variant tree). * any desired loading states (loading file) * any desired switch states (topology file) Non-redundant storage and management of variants. Multi-lingual Graphical User Interface. Integrated chart manager allows to analyze and compare all results from all variants. All computation modules access a shared database. A state of the art library manager with extensive libraries for each element type facilitates data entry. Extensive functions for network statistics and network documentations are available. Each element and node can belong to any independent area and zone. Any number of independent network areas and zones are possible. Option for combining and separating networks. JPG, which can be used in any internet web browser). Graphics can be exported as raster files (e.g. Import of almost any raster and vector graphic files (e.g. Import of a geographic map as a background graphic, for easier schematic capturing. ASCII file or SQL database oriented import/export functions for exchanging network data, topology data and load data are available. Integrated Variant Manager (insert, delete, append, compare variants, compare results, etc.). A coloring tool helps to show which data is needed for which analysis (e.g. The equipment data are entered in dialogs, with plausibility checks provided. OLE functionality: Data and graphic can be moved to and from third party software (like MS-Excel, MS-Word). An element can be moved from one node to an other node without deleting the element. Extensive editing functions like undo, redo, delete, copy, move and zoom for processing the network diagram are available. There is no restriction on drawing sizes and number of nodes and elements. All equipment can be entered graphically and/or table oriented (like in a excel sheet) Most intuitive Graphical User Interface Graphical User Interface and Data Management Application: Transmission Distribution Industrial - Generation Successfully applied all over the world NEPLAN one of the most complete planning, optimization and simulation tool for transmission, distribution, generation and industrial networks. NEPLAN AG Oberwachtstrasse 2 CH 8700 Ksnacht ZH
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Observed toxicities will be summarized, for all dose levels, in terms of type (organ affected or laboratory determination), severity, time of onset, duration, serum concentration of the active leflunomide metabolite, probable association with the study treatment and reversibility or outcome. Incidence of toxicity, graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.03 After completion of study treatment, patients are followed up at 30 days and then every 28 days until disease progression (active follow-up) or every 3 months (long term follow-up). Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients receive leflunomide orally (PO) once daily (QD) on days 1-28. OUTLINE: This is a dose-escalation study. To generate a preliminary ribonucleic acid (RNA)/microRNA (miRNA) and deoxyribonucleic acid (DNA) methylation signature associated with response of MM cells to leflunomide in vivo (mRNA/miRNA and DNA methylation, phase II only) and teriflunomide ex vivo (messenger RNA /miRNA). To explore the potential additive or synergistic effects of combining leflunomide with other classes of Food and Drug Administration (FDA)-approved drugs. To explore the ex vivo cytotoxicity of leflunomide toward primary multiple myeloma (MM) cells, in order to evaluate whether individual ex vivo leflunomide response might be a useful predictor of therapeutic response. To explore the relationship between polymorphisms in the CYP1A2, CYP2C19, or DHODH genes and toxicity/response. To assess the relationship between serum concentration of the active leflunomide metabolite, teriflunomide (A77 1726), and disease response. To characterize the relationship between serum concentration of the active leflunomide metabolite, teriflunomide (A77 1726), and toxicity. To obtain estimates of: response duration, clinical benefit response, overall survival, progression-free survival. To evaluate the anti-myeloma activity of leflunomide, when given as a single agent, as assessed by overall response rate (ORR). To assess the safety and tolerability of leflunomide at each dose level by evaluation of toxicities including: type, frequency, severity, attribution, time course and duration. To determine the maximum tolerated dose (MTD) and recommended phase II dose (RP2D) of leflunomide, when given as a single agent. Leflunomide may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. This phase I/II trial studies the side effects and best dose of leflunomide in treating patients with multiple myeloma that has come back (relapsed) or has not responded to previous treatment (refractory). But from the outside looking in, if PUBG has a case against Fortnite, Borderlands should be suing Destiny, Tomb Raider should be suing Uncharted, Battlefield should be suing Call of Duty, DOTA should be suing League, Everquest should be suing WoW, and so on and so forth. I won’t say that PUBG has no shot at taking on Epic because the law is murky and it’s hard to know how this will play out, depending on who’s rendering judgement. I don’t understand their actual argument that Epic has done something truly immoral/illegal in creating Fortnite: BR, but I suppose that’s the case they have to prove. I’m not going to accuse PUBG of sour grapes here because they genuinely might believe they’ve been wronged in some way. Once upon a time, every first person shooter was a “DOOM clone.” And it seems to me that say, League of Legends was far closer to a clone of DOTA than Fortnite is to PUBG, as the two not only have distinct gameplay with Fortnite’s focus on building, but the two could also not look more visually distinct, despite running on the same engine. The fact is, the video game industry is iterative. And what UI elements can be claimed as unique to PUBG? The.minimap? The…compass? Things that have been in hundreds of games to this point? Hotkeys for weapons? A counter that shows how many players are left? I just don’t understand what PUBG is saying it owns here, but they may have to spell it out in court before we know for sure. The most iconic Fortnite weapon, its various collection of pickaxes, is not a core part of PUBG. And for weapon designs and UI? Again, what is PUBG claiming here? Like most shooters, the vast majority of Fortnite’s weapon designs (and PUBG’s) are based on real life guns, the FAMAS, the M4, and so on. However, these values are lowerthan reductions achieved when strategies are focused on controlling emissions from other vehicle categories.īus rapid transit Emissions Climate change Air quality OpenLCA Biofuels Sustainable urban transport. mix electricity, high voltage APOS - DE, ecoinvent v.3.2, openlca v (i.e. Finally, if TransMilenio buses change from diesel to electricity, C02- eq and PM 2.5 emissions would be reduced by 86% and 88%, respectively. 1 In previous ecoinvent 3.1 versions, this system model was named allocation. The highest emissions of PM 2.5 are given by motorcycles and private cars, and taxis present the highest emissions of NOx. While the lowest emissions of PM 2.5 were achieved by an electric BRT and buses powered by natural gas. Results of this work indicate that public transport buses including BRT produce the lowest emissions of CO 2-eq, CO and NOx. The functional unit is mass of pollutant per kilometer and per passenger transported (mass/km-passenger). Gabi, Fast calculation engine, easily shares models, no and. The impact category climate change (C0 2-eq) and emissions of PM 2.5, CO and NOx were considered. Table 5.1 Three common LCA software package options Software Licensing Data. We used the OpenLCA software, the Ecoinvent database and all the information available in the city to perform this LCA. We applied the life-cycle assessment (LCA) and the well-to-wheels approach. 2016, vol.6, n.3, pp.123-134.ĪBSTRACT This work presents Life Cycle Emissions from the Bus Rapid Transit System (BRT) TransMilenio compared to other modes of passenger transportation in Bogota, Colombia ®. LIFE CYCLE EMISSIONS FROM A BUS RAPID TRANSIT SYSTEM AND COMPARISON WITH OTHER MODES OF PASSENGER TRANSPORTATION. 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If you are sharing your own content please state so. We also encourage disclosing permissions such as if you had permission to post, does the artist allow further reposting or link sharing etc. should be credited with the minimum of giving the creator’s name in the post title and link to the source in the post or as a comment or indicated somewhere if it is your original content. Your thoughts should be left as a comment and not be the post title.Ĭredit & source fan art, cosplay, and labour: Fanart, cosplay, fan labour etc. blog site name, “YouTube”,ĭo not share as a screenshot of the content. The title must be the content name and include the content creator’s name or the platform i.e. Click here for our flair guide to be sure you use them properly.Īlso all spoilers must be tagged for new media, namely Resident Evil: Village and the Netflix series once they releaseīlogs must be links, titled as the content name, and include the creator’s or platform name: Non-official press blog articles, YouTube videos, twitter threads, non-reddit hosted content etc. Use post flairs & mark spoilers: All posts must be correctly flaired. Keep comments on topic, maintain proper Reddiquette, do not engage in incivility, persistent toxicity/disdain, racism, xenophobia etc. The consensus is that the devs managed to craft an alternate universe that is just as interesting as the MCU's Guardians and easily worth expanding on for future instalments.Maintain civility & Reddiquette: Keep this sub fun and lighthearted. Right now, Guardians of the Galaxy is hovering at 81 on Metacritic with an 82 at OpenCritic. Here's what other leading critics are saying about Eidos Montreal's latest take on the now-iconic characters: It's far more Marvel's Spider-Man than Avengers. It's still an experience not to be missed, so you should certainly give it a try. However, some of the game mechanics, unfortunately, feel dated, holding us back from giving it a higher score. Our review for the GotG game also went live recently, highlighting the project's strong sides such as the exciting original story, perfect soundtrack, always funny jokes, and wealth of heart. Related: Guardians Of The Galaxy Gets Why Marvel's Avengers Was A Failure So far, critics seem to agree that Star-Lord's journey is worth your time, despite some teething issues.ĭespite some fears that Guardians would go terribly wrong ( especially given that it's launching in the shadow of Marvel's Avengers), everything seems to have gone smoothly for GotG's development - judging by the first reviews, developer Eidos Montreal has created one of 2021's most pleasantly surprising projects. Marvel's Guardians of the Galaxy launches tomorrow so it's time to find out what major gaming outlets think about the new story-driven action-adventure. New USB drivers for enhanced PC compatibility and stability. New CODES file, now with over 13, 000 fault code and measuring value texts. Adds drop-box function selection in Basic Settings and Adaptation. Modified SRI Screen to show more info and force user to select a job before proceeding. 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